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Sixty-four consecutive patients with clinically or laboratory-supported definite multiple sclerosis(MS)were evaluated prospectively for evidence of primary Sjogren's syndrome(SS).This diagnosis was established when a patient had objective keratoconjunctivitis sicca,xerostomia,or both together with positive labial salivary gland biopsy.We found 2 patients(3. 1%)with clinical evidence of primary SS.Whether this association is fortuitous or whether there is pathogenetic linkage between MS and primary SS remains to be established. |
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